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Tizanidine is a medication that is used to treat muscle spasticity due to spinal cord injury or multiple sclerosis. Effectiveness appears similar to baclofen or diazepam. It is taken by mouth. Common side effects include dry mouth, sleepiness, weakness, and dizziness.

Other names for this medication:
Tizanidine, Zanaflex, Ternelin, Tizan, Tizanidina,

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Tizanidine is used to relieve the spasms and increased muscle tone caused by multiple sclerosis (MS, a disease in which the nerves do not function properly and patients may experience weakness, numbness, loss of muscle coordination and problems with vision, speech, and bladder control), stroke, or brain or spinal injury. Tizanidine is in a class of medications called skeletal muscle relaxants. It works by slowing action in the brain and nervous system to allow the muscles to relax.

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In this review, past and current studies on lipoproteins and similar alternative drug carriers are discussed regarding their suitability as agents to deliver drugs, primarily to cancer cells and tumors. These observations suggest that the trophic activities of NT-3 in the mammalian nervous system might be mediated by different TrkC receptor isoforms. Anti-liver autoantibodies or lymphocyte-reactive alloantibodies were detected respectively without cell-mediated immunity against liver antigen or lymphocytotoxic activity.

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We show the ability of bisphosphonate to prevent the recurrence of urolithiasis. As many of these women have children, increased attention is being given to the types of employer-sponsored benefits offered to workers, especially assistance for those with sick children. Relationship between severity of obstructive sleep apnea syndrome and retinal nerve fiber layer thickness. It was found that allosensitized CTL are more efficient at inducing BSM, or MT-2, cell growth inhibition than LAK cells.

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This and other studies report a high rate of orphan spoligotypes, which highlights the need for genotyping implementation as a routine technique for better understanding of M. In particular, we discuss the importance of identifying incomplete forms of the syndrome, such as those presenting with predominantly ocular manifestations, as is in our case.

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The key pathophysiologic factor may be the increase of gut-derived non-transferrin bound iron liganded to low-molecular mass organic molecules. However, intentional and unintentional misuse and overdose using transdermal opioid patches has been widely reported in the literature. Contribution to the analysis of the postirradiation repair kinetics early after whole-body lethal gamma irradiation in rats. Quality of life measurement in patients with hypertension in Cyprus.

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A study on the image contrast of pseudo-heterodyned scattering scanning near-field optical microscopy. The potentially curable prostate cancer patient and the pathways leading to diagnosis and treatment. The latter had a poor prognosis, which might be improved by adjuvant therapy, although a suitable regimen has not been established. Cortico-cerebellar abnormalities in adolescents with heavy marijuana use. Surgical areas have long been considered risky with regard to occupational exposures to blood-borne pathogens.

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These findings supported the effectiveness of this exercise protocol in decreasing the intensity of shoulder pain which interferes with functional activity in wheelchair users. Moreover, the Chinese nasal anthropometric measurements in this study are broader and flatter than those reported for North American Caucasians. To classify the relationship of the sagittal root positions of the maxillary anterior teeth to their respective osseous housings, and to measure the thickness of facial and palatal alveolar bone by cone-beam computed tomography (CBCT). Predictive value of clinicopathological markers for the metachronous bladder cancer and prognosis of upper tract urothelial carcinoma. In patients with tumor recurrence, a second resection resulted in long-term survival.

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However it should not be the only technique used for these proposes. HMGB1 may also provide a novel link for brain-immune communication leading to post-stroke immunomodulation.

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Analysis of ocular samples by this broad-range real-time PCR method can be utilized for rapid diagnosis of patients suffering from unknown intraocular disorders such as idiopathic uveitis/endophthalmitis. Our results showed that the timing and duration of submersion affected the number and percent cover of natives and NIS, as well as assemblage composition. Adult respiratory distress syndrome in obstetrics and gynecology.

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This paper reports on the plant use of laypeople of the Oromo in Southern Ethiopia. In-depth understanding of hepatic physiology is essential to properly address the postoperative issues.

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A fluorometric method for the assay of rat brain N-methyltransferase (NMT) has been developed using rat brain 9000 x g supernatant fluid as an enzyme preparation. Thus, RLA rats are considered as a genetic model of vulnerability to stress-induced depression whereas RHA rats are a model of resilience to that trait.

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The characteristics of a modern chromatographic method for the determination of herbicide residues are summarized and trends in the development and combination of current GC and LC methods discussed. Comparison of a Web-Based Teaching Tool and Traditional Didactic Learning for In Vitro Fertilization Patients: A Preliminary Randomized Controlled Trial. To prospectively evaluate the impact of parathyroidectomy on swallowing-related quality of life using the Swallowing Quality Of Life (SWAL-QOL) validated outcomes assessment tool.

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The cytotoxic effect of the complex was comparable to that of cisplatin, and mediated by apoptosis associated with oxidative stress, mitochondrial depolarization and caspase activation. This effect was more evident in patients with increased risk of postoperative pulmonary complications. There is little specific information concerning the method and the efficacy of sharing information between occupational health physicians and psychiatrists regarding the employment status and medical history of their patients with mental illnesses.

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Intramedullary neurenteric cysts not associated with other spinal anomalies are very rare especially in the conus medullaris region. We previously designed a p53 protein, p53FG, with amino substitutions S121F and V122G targeting loop L1. Effect of cycle time on polyhydroxybutyrate (PHB) production in aerobic mixed cultures. Leukocyte 8-OHdG may add power beyond the traditional factors in predicting ICH outcome and thus may be used as an independent surrogate for clinical ICH study. However, further work is needed to establish the genetic toxicology and immunohistochemistry of caspase-3 and claudin-1.

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Dynamics of the bacterial genome: deletions and integrations as mechanisms of bacterial virulence modulation. Giardia duodenalis is an important zoonotic pathogen in both public and veterinary health, and has been genotyped into at least eight assemblages (A-H), each with a distinct host range. Motivated by a surface-based group-wise particle correspondence method, we developed a novel system that takes such particles to the image domain, while keeping the spirit of the method similar. Diphenhydramine, even at a low dose, reduces the strength of vertigo at ultra-high static magnetic fields, may be used preventively, and could pave the way to even higher field strength.

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Targeting high-level quantum mechanical and experimental crystal data, the new parameters were optimized in a hierarchical fashion designed to maintain compatibility with the remainder of the CHARMM additive force field. Selective inhibitor of protein kinase C (PKC - chelerythrine) does not change the depression of the ACh-current. Although patients with simultaneous esophageal cancer and gastric cancer have been reported, it is often difficult to diagnose the coexistence of gastric cancer preoperatively due to the presence of esophageal stenosis.

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There were no objective responses as defined by standard criteria. Modulation of cardiovascular effects produced by nitric oxide and ionotropic glutamate receptor interaction in the nucleus tractus solitarii of rats. Prediction of coronary artery lesions in unstable angina by iodine 123 beta-methyl iodophenyl pentadecanoic acid (BMIPP), a fatty acid analogue, single photon emission computed tomography at rest. Building a disease knowledge environment to lay the foundations for in silico drug discovery and translational medicine. Bone and cartilage are major weight-bearing connective tissues in human and possesses utmost vulnerability for degeneration.

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High levels of markers of oxidative DNA damage excreted in the urine indicate elevated levels of oxidative stress, but can also reflect a high level of efficiency of the processes that work to repair this damage (oxidative stress can be high and the repair processes eliminate its effects). The association of PEG with upper gastrointestinal bleeding (UGIB) and role of gastroesophageal reflux disease (GERD) in relation to UGIB in patients with PEG are not well known. Healthcare providers interested in starting a joint venture should consider five basic formats and some guidelines for developing them. This article provides a history of tobacco, from the sacred use by Native Americans, to the commercialism of tobacco in North America. The purpose of this study was to quantify the influence of some of the predisposing, enabling, and healthcare need variables on dental health services utilization (DHSU) among Mexican adolescents.

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However, mRNA for these inhibin subunits was not detected in exocrine pancreas. Psychological disturbance in parentally bereaved children and surviving parents, and statistical associations between sample characteristics and service provision. LMB treatment, on the other hand, rapidly induced the nuclear entry of RanBP1, a factor involved in the active nucleocytoplasmic transport, although the treatment did not interfere with a nuclear localization signal-dependent transport system within 7 h. Elevated serum fetuin-A levels are associated with grades of retinopathy in type 2 diabetic patients.

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The a-MBM-DOX nanosystem showed an efficient self-delivery, enhanced enzymatic stability, excellent target selectivity, and high drug-loading capacity. Yet the mechanism of disease progression with respect to the complement system in these maladies is not fully understood. A pull-down assay indicated that the interaction of full-length TIF2 with hERbetaV320G was weaker than with hERbetawt. Expression of adhesion molecules and mucins in human and rhesus macaque gastrointestinal epithelial cells. P760 is an MR imaging contrast agent characterized by low diffusion, a blood pool effect soon after low-dose administration, and fast elimination.

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Clinical pathways for LBP need to be further developed and investigated as a means to facilitate guidelines-concordant practice and improve patient outcomes. Symptoms in five of six patients subsided after laparoscopic removal of the oviduct. The significance of PD-L1 expression and human leukocyte antigen class I (HLA class I), recognized by CD8 T cells, in the prognosis of patients with HCC remains to be determined. Leg alignment reactivity: an increase in leg alignment discrepancy (yes or no) following a diagnostic intervention. Newer direct-acting antiviral agents such as ABT-450 promise effective and durable suppression of HCV with interferon/ribavirin-free all-oral regimens.

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The finding of flavivirus NS4B dimerization and the mapping of regions important for NS4B dimerization provide the possibility to inhibit viral replication through blocking NS4B dimerization. Evening primrose oil proved to have a stabilising effect on the stratum corneum barrier, but this was apparent only with the water-in-oil emulsion, not the amphiphilic emulsion. Double layer immunofluorescence and peroxidase anti-peroxidase (PAP) methods gave similar results.

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Comparison of classification methods for P300 brain-computer interface on disabled subjects. Neurosteroids are synthesized both in brain and peripheral steroidogenic tissue from cholesterol or steroidal precursors. Evaluation with transoesophageal echocardiographic and real time three-dimensional imaging. In both cases galanin causes hyperpolarization (at high concentrations) and prolongs monoamine-induced outward currents (at low concentrations), thus modulating activity in two systems of importance for many brain functions including mood regulation. This G deletion results in a frameshift mutation producing a premature stop codon in exon 25 of ALK tyrosine kinase domain.

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A national paradox: satisfied with their own care, Americans want to overhaul the system. However, limited echocardiographic windows and logistical difficulties make conventional echocardiography during interventional catheterization impractical and of limited value. The mixture of equal volume of antiserum and FXIII was intradermally injected into dorsal skin of guinea pig after Evans blue injection, and 15 minutes later the quantity of Evans blue at the each injection site was determined.

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Perirenal fat has been recently associated with CV risk in adults. DNA inhibits C1q binding to IgG immune complexes (ICs) through binding to C1q rather than to IgG, as seen from two lines of evidence.

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Lymphogranuloma venereum: an old, forgotten re-emerging systemic disease. During the experimental session measures of ad lib smoking behavior, tobacco withdrawal, craving for cigarettes, and cognitive performance were obtained. The LD78beta isoform of MIP-1alpha is the most potent CCR5 agonist and HIV-1-inhibiting chemokine. Here, we identified four allelic rice mutants, s2-89, xd151, xd281 and xd425, which exhibited reduced width of spikelet, especially in the apical region.

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Three classes of fetal weight formulas (linear, quadratic, and cubic) were fitted to the data using stepwise regression analysis. VCs sometimes coexist with conventional SCCs, and in these instances they are associated with a higher recurrence rate than pure VCs.

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Do public health practitioners have satisfactory access to important information sources? In AL amyloidosis, the importance of right ventricle (RV) involvement has recently been underlined and its role in predicting prognosis has been emphasized. The predictive value of urinary vanillylmandelic acid testing in the diagnosis of phaeochromocytoma at the University Hospital of the West Indies.

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It is processed so that the epidermis and all dermal cells are removed without disruption of the collagen matrix, rendering the material immunogenically inert and resistant to calcification. This approach allows one to obtain a consistent and rather general understanding of the effects of ions on solvent properties.

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Ultrasound determination of chorionicity is most reliable before 14 weeks and subsequently reduces in accuracy with advancing gestation. Plasma histamine and tryptase concentrations were measured during 24 hours after 8 open food challenges in 7 other patients with suspected food allergy. Finally, it is important not to become complacent about the ongoing efforts towards inclusiveness and greater participation.

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A soluble protein with a molecular weight of approximately 52,000 Da (from SDS-polyacrylamide gel electrophoresis) was purified from porcine ciliary body, vitreous body and retina by ammonium sulfate fractionation, Sephacryl S-300 gel filtration, and DEAE-cellulose ion exchange chromatography. The most devastating consequence of craniofacial FD (CFD) is loss of vision due to optic nerve compression (ONC). Transcatheter embolization of type I endoleaks using Onyx is a simple, safe, and sustainable treatment option with a high primary success rate for cases in which stent-graft extension is not possible. Randomized controlled trials are under way to further evaluate this technique. A 74-year-old man with chronic kidney disease underwent EVAR with an Endurant stent-graft using CO2 angiography to guide graft placement.

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Mammalian elongin C interacts with both elongin A and elongin B, as well as with the von Hippel-Lindau tumor suppressor protein VHL. The aim of this study was to evaluate the possible role of prostacyclin (PGI2) in the pathogenesis of hypertension in spontaneously hypertensive rats (SHR). Research continues in discerning exactly how granulocyte transfusion work, in preservation of granulocytes, and in delineation of immunologic phenomena affecting the efficiacy of such therapy. Hyperemic flow was induced by intravenous dipyridamole pharmacologic stress.

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The results suggest that improved blue-light transmission following cataract surgery has a beneficial effect on cognitive function. We found no evidence for active transmission of LF in cities, where internally displaced persons from rural areas lived for many years during the more than 10 years conflict in Sierra Leone and Liberia. Treatment consisted of docetaxel, 100 mg/m2, as a 1-hour intravenous infusion repeated every 21 days, with protocol-specified dose reductions for toxicity. Detection of aberrant hypermethylated spastic paraplegia-20 as a potential biomarker and prognostic factor in gastric cancer. No unambiguous relationships between thymallins, coregonins, and salmonins it was possible to establish.

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UClncR: Ultrafast and comprehensive long non-coding RNA detection from RNA-seq. Thorough assessment of transgenic (Tg) mouse lines that replicate this process is critical for establishing the models used for testing anti-tau therapeutics in vivo.

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Patients identified retrospectively were approached for recruitment. The changes in the eyes of whites displayed a nasal-temporal axial asymmetry, reflecting greater enlargement of the nasal retinal sector.

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In the second study, mold contamination was evaluated on levels 6 through 19 of an office building with a history of water problems and health complaints. In conclusion, MDCT can be used noninvasively with a lower radiation dose for the assessment of restenosis in CABG patients. (3) The embryo-responsive polyomavirus F101 enhancer also stimulated promoter activity, but only after formation of a 2-cell embryo.

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Increased risk of acute pancreatitis among tetracycline users in a Swedish population-based case-control study. Here, a enacard enalapril side effects conduction micropump with symmetric planar electrode pairs prepared on flame-retardant glass-reinforced epoxy (FR-4) copper-clad laminate (CCL) is fabricated. Clinical and Genetic Evaluation of a Cohort of Pediatric Patients with Severe Inherited Retinal Dystrophies. Heme binding leads to different exposure of the tryptophan residue at position 51 to the surface of the protein.

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The data derive from field work in Cambodia in 1965-66 and from several shorter anticol lozenges ingredients for pizza periods of fieldwork in the mid-1980s among Cambodian refugees in France, Thailand, Australia, Germany and the United States. Furthermore, clearance and distribution of radiolabeled human LDL in different tissues were investigated in the rat after ACTH treatment. The behaviors in open-field test, hormons, metallothionein (MT) and the antioxidant ability of the rats were detected. South African guidelines for the management of Gaucher disease, 2011. Preclinical chemotherapeutic tumor models of common childhood cancers: solid tumors, acute lymphoblastic leukemia, and disseminated neuroblastoma.

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Osteotech DFDBA particles demonstrated significantly faster degradation when compared with all other bone grafts. preassembled head used in cortical bone trajectory: Can pars and pedicle fractures be prevented in osteoporotic bone? Significant correlation between meibomian gland dysfunction and keratitis in young patients with Demodex koi apna sa serial watch online brevis infestation.

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The purpose of our study was to determine the prevalence of social phobia in a primary care clinic, the rates of comorbidity with other anxiety and mood disorders, the extent of disability, and patterns of healthcare utilization. The layout of the letter should be inviting, which is readily achievable through judicious use of tab zolfresh indications for albuterol word processing. Has Massachusetts health care reform worked for the working poor? A series of concise recommendations is presented to guide trialists when considering undertaking causal analyses.

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The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I. alprazolam pill number 512 Pain assessment in children is often poorly executed following acute injury. There was a negative correlation between age and positive scores of the Positive and Negative Syndrome Scale. CURRENT PEER REVIEW SYSTEMS: A PROBLEM FOR INNOVATIVE APPROACHES IN SCIENCE. To study temporal trends in short- and long-term outcome after myocardial infarction (MI) according to diabetes status.

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Somatic symptoms in adolescence predicted depression and other adult mental disorders regardless of the presence of amlodipine/valsartan dosage index adolescent depression. The clinical range, from tuberculoid to lepromatous leprosy is a result of variation in the cell-mediated immune response, with a chronic inflammation in skin and peripheral nerves.

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The results indicate that the untranslated state cannot be attributed to poor initiation efficiency. Structural basis and target-specific modulation of ADP sensing by the Synechococcus elongatus PII amantan multiple sclerosis symptoms signaling protein. Distribution of polychlorinated biphenyls in soil around three typical industrial sites in Beijing, China.

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To assess arterial wall inflammation in HIV, using 18fluorine-2-deoxy-D-glucose positron emission tomography (18F-FDG-PET), in relationship to traditional and nontraditional risk markers, including soluble CD163 (sCD163), a marker of monocyte and macrophage activation. Due to the lower transmit amplitude and enhanced backscatter from microbubbles, the in vivo signal to clutter ratios for both the fundamental (-11 dB) and harmonic (-4 dB) vascular flow signals were greater than with conventional power Doppler (-51 dB) without contrast agent. Blood glucose level and protein content of discrete brain regions were also estimated. Perhaps because of the limitations of the clinical documentation shown to anesthesia providers and OR nurses in the current vignette study, more evidence needs to be gathered to demonstrate the criterion-related validity of the QWAT difficulty items for assessing the rabeloc rd capsule stain workload of nonsurgeon OR clinicians. Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo.

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Similarly, MFB self-stimulation was enhanced by ipsilateral habenular lesions. The environmental plan provides a mathematical simulation of the sediment-dispersion to evaluate the possible impact on the meadow. A 17-fold sustained reduction in the rate of incorrectly addressed test reports was achieved with faster turnaround time, no significant expenditure of funds, and no changes in staff, equipment, or the laboratory information system. Also we provide the first evidence that some members of the GmPAP gene family are possibly involved in the response of plants to symbiosis parkinson's medications ropinirole drug with rhizobia or arbuscular mycorrhizal fungi under P-limited conditions.

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Although a poor indicator of how a dose of bactrim to treat uti cellulase preparation will perform on biomass, the filter paper unit (FPU) still finds wide use in the literature as an apparent measure of performance efficacy. Assessing the extent of non-aggressive cancer in clinically detected stage I non-small cell lung cancer. The LNalpha1 chain transgene not only reversed the appearance of histopathological features of the disease to a remarkable degree, but also greatly improved health and longevity of the mice. The use of 1.32 Nd:YAG laser in neurosurgery: experimental data and clinical experience from 70 patients.

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In this review, oratil 250 uses we will examine the concept of mucosal healing, including its definitions and assessment techniques, and will evaluate the data regarding the potential benefits of achieving mucosal healing in the treatment of IBD. Evidence of a receptor for hyaluronic acid on a lymphocyte subpopulation. Biliary atresia with associated complicated anorectal and urogenital malformations. Oxygen and/or ventilatory support may be necessary for life-threatening conditions.