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Hepatitis C virus-induced autophagy is independent of the unfolded protein response. No benefit of saxagliptin on cardiovascular outcomes in type 2 diabetes mellitus: potential explanations.

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Genetic analysis of HLA- and HPA-typing in idiopathic (autoimmune) thrombocytopenic purpura patients treated with cepharanthin. The pretreatment with a single dose of olive, extra virgin olive and canola oils caused a statistically significant decrease in the total of chromosomal aberrations and abnormal metaphases induced by cisplatin when compared with the groups treated with cisplatin alone. Altered signaling triggered by ligation of the TCR/CD3 receptor in T lymphocytes from patients with systemic lupus erythematosus: the road from anergy to autoimmunity. Although the biological activities of TGF-beta 1, TGF-beta 2, and TGF-beta 3 are similar at the level of cell culture, distinct in vivo functions for these molecules are emerging.

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A male case of sclerosing peritonitis of unknown cause, associated with keratoconjunctivitis sicca, pleurisy, and secretory otitis media, is presented. One hundred horizontally sectioned human temporal bones (TB) were examined under light microscopy. We expect as that structural information for the tight junction proteins becomes more widely available and the molecular modeling algorithms improve, so will our understanding of the relevance of phosphorylation changes at single and multiple sites in tight junction proteins. Operative vaginal delivery and neonatal and infant adverse outcomes: population based retrospective analysis. Our analysis revealed distinctive species, tissue and assay-dependent recognition patterns of different antibodies.

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The emergence of HBe-minus hepatitis B virus (HBV) mutants, usually through a UAG nonsense mutation at codon 28 of the precore region, helps the virus to survive the anti-HBe immune response of the host. Patients were assessed for sociodemographic characteristics, type of spondyloarthritis, time since diagnosis and disease activity, non-steroidal anti-inflammatory drug use, HLA-B27 positivity, creatinine and urea serum levels, major comorbidities, hematuria and proteinuria. By contrast, a new class of comparative methods relies on comparing genomic sequences from evolutionary related organisms to each other.

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Free-Standing Metal Oxide Nanoparticle Superlattices Constructed with Engineered Protein Containers Show in Crystallo Catalytic Activity. Overexpression of SSAT in kidney cells recapitulates various phenotypic aspects of kidney ischemia-reperfusion injury. Impaired cardiac function and sleep-disordered breathing (SDB) are associated with progression of chronic kidney disease (CKD) in heart failure (HF) patients.

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Bison and bovine rectoanal junctions exhibit similar cellular architecture and Escherichia coli O157 adherence patterns. All subjects received standardized aminophylline and steroid therapy. We uncovered complex combinations of single nucleotide polymorphisms and CNVs in genes expressed in both neurocardiac and respiratory control pathways, including SCN1A, KCNA1, RYR3, and HTR2C. (1) Hypoxia and A2E each decreased viability of RPE cells in a time-dependent manner. A heterodyne interference microscope arrangement for full-field imaging is described.

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Perceptions of ethnic and cultural factors in the delivery of services in the treatment of sickle cell disease. Preliminary studies suggest that an alteration in pulsewave oscillations induced at small artery branch points serves as a guide to endothelial dysfunction and reduced nitric oxide bioactivity. Mechanically-ventilated patients with TBI developed NED in addition to changes in muscle structure during their stay in the ICU. A case study illustrating the application of the procedure for aural rehabilitation is presented.

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Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise. This preliminary study aims to determine the differentially expressed proteins from chondrogenic differentiated multipotent stromal cells (cMSCs) in comparison to undifferentiated multipotent stromal cells (MSCs) and adult chondrocytes (ACs). This multicenter cross-sectional study was conducted at ten outpatient departments at Chinese general hospitals.

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Practice-related improvements in postural control during rapid arm movement in older adults: a preliminary study. Cerebral venous sinus expansion in post-lumbar puncture headache. The aim of this systematic review is to critically appraise controlled clinical trials investigating the role of FETO in moderate and severe isolated CDH and explore whether this treatment is justified within our region. Endoplasmic reticulum stress induces a caspase-dependent N-terminal cleavage of RBX1 protein in B cells. The findings of a similar abnormality in some cases of non-immune thrombocytopenia suggested that the reduction in suppression observed in chronic ITP was unlikely to be a primary event in disease pathogenesis, although it could well contribute to the ongoing autoimmune response.

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Robotic-assisted angioplasty: current status and future possibilities. We illustrate the approach by random regression mixed models on 1115 observations of clutch sizes and laying dates of 361 female Ural owl Strix uralensis collected over 31 years to show that (1) there is variation across individuals in the slope of their clutch size-laying date relationship, and that (2) there is selection on the slope of the reaction norm between these two traits.

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Khat chewing is often associated with tobacco use with impacts on health. Hyperlipoproteinemia in uremic patients, most commonly of the type IV variety, responds to dietary methods (reduction of carbohydrate content, increase in P/S ratio) or pharmacological intervention. Pasteurella multocida-infected expanded polytetrafluoroethylene hemodialysis access graft. Two shRNAs efficiently inhibited mRNA and protein expression of MDR1 in SGC7901-MDR1 cells.

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